Showing posts with label medicine. Show all posts
Showing posts with label medicine. Show all posts

Fighting the Black Death



The Bubonic Plague, also known as the Black Death, killed at least 75 million people on three continents. Described as the most lethal epidemic in history, the plague began in China in the 1330s and made its way through Europe from 1346 to 1353. In those times, physicians didn't know what was causing the disease to spread, but they did know it was highly contagious. To provide medical care and to protect themselves, doctors of the time invented the medieval version of a hazmat suit. They were specifically hired by towns that had many plague victims in times of epidemics. Since the city was paying their salary, they treated everyone: both the rich and the poor.


The protective suit consisted of a heavy fabric overcoat that was waxed, a mask with glass eye openings and a cone nose shaped like a beak to hold scented substances and straw.

Some of the scented materials were ambergris, lemon Balm (Melissa officinalis), mint (Mentha spicata L.) leaves, camphor, cloves, laudanum, myrrh, rose petals, storax. This was thought to protect the doctor from miasmatic bad air.The straw provided a filter for the "bad air". A wooden cane pointer was used to help examine the patient without having to touch them. It was also used as a means of repenting sins, as many believed that the plague was a punishment and would ask to be whipped to repent their sins.




Chronicles and letters from the time describe the terror wrought by the illness. In Florence, the great Renaissance poet Petrarch was sure that they would not be believed: ‘O happy posterity, who will not experience such abysmal woe and will look upon our testimony as a fable.’ A Florentine chronicler relates that,

    All the citizens did little else except to carry dead bodies to be buried [...] At every church they dug deep pits down to the water-table; and thus those who were poor who died during the night were bundled up quickly and thrown into the pit. In the morning when a large number of bodies were found in the pit, they took some earth and shovelled it down on top of them; and later others were placed on top of them and then another layer of earth, just as one makes lasagne with layers of pasta and cheese.


The tragedy was extraordinary. In the course of just a few months, 60 per cent of Florence’s population died from the plague, and probably the same proportion in Siena. In addition to the bald statistics, we come across profound personal tragedies: Petrarch lost to the Black Death his beloved Laura to whom he wrote his famous love poems; Di Tura tells us that ‘I [...] buried my five children with my own hands’.


Importantly, plague was spread considerable distances by rat fleas on ships. Infected ship rats would die, but their fleas would often survive and find new rat hosts wherever they landed. Unlike human fleas, rat fleas are adapted to riding with their hosts; they readily also infest clothing of people entering affected houses and ride with them to other houses or localities. This gives plague epidemics a peculiar rhythm and pace of development and a characteristic pattern of dissemination. The fact that plague is transmitted by rat fleas means plague is a disease of the warmer seasons, disappearing during the winter, or at least lose most of their powers of spread. The peculiar seasonal pattern of plague has been observed everywhere and is a systematic feature also of the spread of the Black Death. In the plague history of Norway from the Black Death 1348-49 to the last outbreaks in 1654, comprising over thirty waves of plague, there was never a winter epidemic of plague. Plague is very different from airborne contagious diseases, which are spread directly between people by droplets: these thrive in cold weather.

With no accurate knowledge about the disease and the way it was spread, what could be done in the face of such horror? While many fled, others waited. Indeed, under Islamic doctrine, plague - being the will of God - was to be endured and fleeing was forbidden. Others, turning to religion for protection, formed themselves into wandering groups of penitents. They travelled from town to town, ritually flagellating themselves in public acts of repentance to a God who was clearly very angry. But violence could also be directed outwards. In mainland Europe outsiders and religious minorities - especially Jews - were subject to violent and vicious abuse.

Less disturbing, if equally useless, were the numerous plague ‘cures’. Strapping live chickens around plague buboes or drinking potions laced with mercury, arsenic or ground horn from the mythical unicorn did not help. Nor did carrying sweet-smelling flowers and herbs or ornate pomanders to purify the air. But amid the chaos, the pandemic prompted more useful responses - early public health measures to be expanded and then refined in the coming decades. For the Black Death should not be seen in isolation. It was the main event, a big bang. But it was also the herald for waves of lesser plague outbreaks that appeared regularly until well into the 1700s.

When the Black Death spread through Italy in late 1347, some ports began turning away ships suspected of coming from infected areas. During March the following year, authorities in Venice became the first to formalise such protective actions against plague, closing the city’s waters to suspect vessels, and subjecting travellers and legitimate ships to 30 days’ isolation. This period was extended to 40 days some years later - hence the term quarantine. Further regulations established remote cemeteries for plague victims who in turn were collected, transported and buried in accordance with defined rules. But these measures were too little, too late. Plague took hold and Venetians died in their tens of thousands.



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Ancient dentistry: gold and pain

Going to the dentist today is like spending the day at the spa, at least compared to dentistry thousands of years ago. While you walk into an office for a routine check-up and patiently wait to the sound of calming music and stacks of magazines, Egyptians, ancient Greeks or Etruscans were cringing in pain with massive toothaches and a stomach full of anticipation and dread. 


It is agreed that the oldest of those civilizations that knew something of dentistry was Egypt. The earliest indication of any such knowledge, in Egypt is found in the Edwin Smith Surgical Papyrus. It is dated in the 17th century B.C., even if the original author's first manuscript was produced at least a thousand years earlier, between 2500 and 3000 B.C. 


Egyptian gold wire, 4000 years old.
The two centre teeth are donor teeth 
Attrition was by far the most common affection in ancient Egypt. Caused by the coarse diet (which may also have lacked necessary minerals and vitamins) and the presence of sand, husks, and sometimes even straw, in their bread, many Egyptians suffered from this condition. The skulls and jaws found in burial shafts and tombs almost all show attrition to some degree. This may not sound like a very serious disease, but attrition, when left unchecked, can be a stepping stone to much more severe issues. It can lead to abscesses, inflammation of the gums and jawbone, and tooth loss. Despite a diet free of refined sugar, caries was still fairly well represented amongst Egypt’s pearly whites. Interestingly enough, this disease seemed to have been much more common among the elite than it was among lower classes. This may be attributed to the higher sugar content in the diet of higher class Egyptians. The papyrus has eleven recipes which pertain to oral issues. Four of these are remedies for loose teeth: the tooth in question is either ‘packed’ or ‘filled’ (the translation and therefore our interpretation is a little ambiguous) with a mixture that is akin to a modern day composite filling: a filler agent (ground barley) is mixed with a liquid matrix (honey) and an antiseptic agent (yellow ochre). This is either used as an actual filling, or as a splint to keep the tooth in place.

Etruscan people were the first to take basic work in the mouth to a more artistic level. Etruscan's were incredibly intelligent people who were always striving to increase their knowledge and improve their image. Luxury was important to them, and they continued to test boundaries in the medical field. The courage to travel across sea to trade with other civilizations is proof of their industrious and courageous personalities. Using the knowledge of dentistry they learned from travel, they began to experiment with filling gold teeth. In one preserved mouth, gold bands were wrapped around the teeth and cemented by soldering with heat. Human and animal teeth were used as artificial teeth and held in place by gold bands. Performed around 700 B.C this is the first time in history a form of prosthetics was ever used in the mouth, and would be the only use for many years.

Etruscan, 4th century BC
While exploring and researching Greek mummies, archeologists have learned a mouthful of information on ancient dentistry. One mummy was found with many devastating dental problems. It is hard to imagine that cavities could kill you, but this mummy died from a basic sinus infection caused from a life of painful cavities. This mummy was a young man somewhere in his twenties. Greek dentists struggled to stop and cure his cavities. Linen soaked in medicine was packed in the holes in his teeth in an attempt to relieve the pain. Cloth in the tooth prevented food from entering and festering in the area. Greeks prided themselves in their strength and ability to handle pain. So, when cavities were found in the teeth, Greeks would often deal with the pain rather than have the tooth pulled. Losing a tooth would be a great loss and the pain was a small price to pay.


But the oldest example of therapeutic dentistry was found in Slovenia. The tooth is 65 centuries old and was part of a man's jaw. The jaw, which once belonged to a 24- to 30-year-old man, included a left canine tooth possessing a vertical crack in its hard enamel and softer dentin layers. The researchers found beeswax had been applied to the left canine at about the time of the man's death.

Generally speaking dentists had a lot work with ancient people. All the treatments were extremely painful. 

Etruscan denture with false teeth



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2,000-year-old roman face cream with visible, ancient fingermarks

The six-centimetre-wide canister, currently on display in the Museum of London, was discovered in July 2003 by Pre-Construct Archaeology at the site of a Roman temple complex dedicated to the god Mars Camulus. It dates from approximately 150 AD.


The contents were so well preserved (you can still see finger marks in the cream) that the team was able to recreate the product from fresh ingredients. The main constituent of the cream was animal fat mixed with starch and tin oxide.

This rare find was then chemically analyzed by University of Bristol’s Richard Evershed, who has a quirky research niche: Figuring out the composition of ancient medical, food and cosmetic concoctions, usually by studying residues leftover on old pottery. (He made news last December by reporting that the fatty deposits on pieces of ancient Polish pottery are Northern Europe’s oldest evidence of cheese-making.)

So what precisely was in the creamy white ointment?

In a 2004 Nature paper, Evershed’s team announced that “the Londinium cream” was primarily made up of animal fat, probably from cattle or sheep. They also detected starch, which was likely isolated by boiling roots and grains in water. In addition, the cream contained a tin dioxide mineral called cassiterite with the chemical formula SnO2.

This cream had a pleasant texture when rubbed into the skin. Although it felt greasy initially, owing to the fat melting as a result of body heat, this was quickly overtaken by the smooth, powdery texture created by the starch. Remarkably, starch is still used for this purpose in modern cosmetics. The addition of SnO2 to the starch/fat base confers a white opacity, which is consistent with the cream being a cosmetic. Fashionable Roman women aspired to a fair complexion, and the Londinium cream may have served as a foundation layer
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